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Evaluating a Living Donor With Rheumatoid Arthritis for a Recipient With End-Stage Renal Disease From Antineutrophil Cytoplasmic Antibodies Associated Vasculitis

A 60-year-old Caucasian female with sero-positive rheumatoid arthritis (RA) was evaluated as a potential kidney donor for her brother-in-law with end-stage kidney disease (ESKD) secondary to c-antineutrophil cytoplasmic antibody (c-ANCA) associated vasculitis (AAV) and membranous nephropathy (MN). W...

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Autores principales: De Souza, Luisa M, Ghahramani, Nasrollah, Abendroth, Catherine, Kaur, Gurwant
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8527875/
https://www.ncbi.nlm.nih.gov/pubmed/34692328
http://dx.doi.org/10.7759/cureus.18117
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author De Souza, Luisa M
Ghahramani, Nasrollah
Abendroth, Catherine
Kaur, Gurwant
author_facet De Souza, Luisa M
Ghahramani, Nasrollah
Abendroth, Catherine
Kaur, Gurwant
author_sort De Souza, Luisa M
collection PubMed
description A 60-year-old Caucasian female with sero-positive rheumatoid arthritis (RA) was evaluated as a potential kidney donor for her brother-in-law with end-stage kidney disease (ESKD) secondary to c-antineutrophil cytoplasmic antibody (c-ANCA) associated vasculitis (AAV) and membranous nephropathy (MN). With little to no data supporting or contradicting this unique scenario, in addition to the varying viewpoints expressed by the different specialists, our multidisciplinary transplant committee encountered a difficult decision of whether to approve a candidate with RA for a living kidney donation or not. As a result, we carried out a careful literature review addressing aspects of recipients’ outcomes following kidney transplants from a living donor with RA, especially when the recipient has AAV, living donor’s short- and long-term outcomes post kidney donation, renal disease in AAV and RA, and maintenance of disease remission.
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spelling pubmed-85278752021-10-22 Evaluating a Living Donor With Rheumatoid Arthritis for a Recipient With End-Stage Renal Disease From Antineutrophil Cytoplasmic Antibodies Associated Vasculitis De Souza, Luisa M Ghahramani, Nasrollah Abendroth, Catherine Kaur, Gurwant Cureus Internal Medicine A 60-year-old Caucasian female with sero-positive rheumatoid arthritis (RA) was evaluated as a potential kidney donor for her brother-in-law with end-stage kidney disease (ESKD) secondary to c-antineutrophil cytoplasmic antibody (c-ANCA) associated vasculitis (AAV) and membranous nephropathy (MN). With little to no data supporting or contradicting this unique scenario, in addition to the varying viewpoints expressed by the different specialists, our multidisciplinary transplant committee encountered a difficult decision of whether to approve a candidate with RA for a living kidney donation or not. As a result, we carried out a careful literature review addressing aspects of recipients’ outcomes following kidney transplants from a living donor with RA, especially when the recipient has AAV, living donor’s short- and long-term outcomes post kidney donation, renal disease in AAV and RA, and maintenance of disease remission. Cureus 2021-09-20 /pmc/articles/PMC8527875/ /pubmed/34692328 http://dx.doi.org/10.7759/cureus.18117 Text en Copyright © 2021, De Souza et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
De Souza, Luisa M
Ghahramani, Nasrollah
Abendroth, Catherine
Kaur, Gurwant
Evaluating a Living Donor With Rheumatoid Arthritis for a Recipient With End-Stage Renal Disease From Antineutrophil Cytoplasmic Antibodies Associated Vasculitis
title Evaluating a Living Donor With Rheumatoid Arthritis for a Recipient With End-Stage Renal Disease From Antineutrophil Cytoplasmic Antibodies Associated Vasculitis
title_full Evaluating a Living Donor With Rheumatoid Arthritis for a Recipient With End-Stage Renal Disease From Antineutrophil Cytoplasmic Antibodies Associated Vasculitis
title_fullStr Evaluating a Living Donor With Rheumatoid Arthritis for a Recipient With End-Stage Renal Disease From Antineutrophil Cytoplasmic Antibodies Associated Vasculitis
title_full_unstemmed Evaluating a Living Donor With Rheumatoid Arthritis for a Recipient With End-Stage Renal Disease From Antineutrophil Cytoplasmic Antibodies Associated Vasculitis
title_short Evaluating a Living Donor With Rheumatoid Arthritis for a Recipient With End-Stage Renal Disease From Antineutrophil Cytoplasmic Antibodies Associated Vasculitis
title_sort evaluating a living donor with rheumatoid arthritis for a recipient with end-stage renal disease from antineutrophil cytoplasmic antibodies associated vasculitis
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8527875/
https://www.ncbi.nlm.nih.gov/pubmed/34692328
http://dx.doi.org/10.7759/cureus.18117
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