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The Frequency of DNA Mismatch Repair Deficiency Is Very Low in Surgically Resected Lung Carcinoma

INTRODUCTION: DNA mismatch repair (MMR) deficiency leads to changes in the length of nucleotide repeat sequences of tumor DNA. In that situation, DNA replicational errors occur and accumulate during DNA replication. As a result, this mechanism frequently affects the coding regions of oncogenes and t...

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Detalles Bibliográficos
Autores principales:	Yanagawa, Naoki, Yamada, Noriyuki, Sugimoto, Ryo, Osakabe, Mitsumasa, Uesugi, Noriyuki, Shiono, Satoshi, Endoh, Makoto, Ogata, Shin-ya, Saito, Hajime, Maemondo, Makoto, Sugai, Tamotsu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8527876/ https://www.ncbi.nlm.nih.gov/pubmed/34692533 http://dx.doi.org/10.3389/fonc.2021.752005

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