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Nucleocapsid mutations in SARS-CoV-2 augment replication and pathogenesis
While SARS-CoV-2 continues to adapt for human infection and transmission, genetic variation outside of the spike gene remains largely unexplored. This study investigates a highly variable region at residues 203–205 in the SARS-CoV-2 nucleocapsid protein. Recreating a mutation found in the alpha and...
Autores principales: | Johnson, Bryan A., Zhou, Yiyang, Lokugamage, Kumari G., Vu, Michelle N., Bopp, Nathen, Crocquet-Valdes, Patricia A., Kalveram, Birte, Schindewolf, Craig, Liu, Yang, Scharton, Dionna, Plante, Jessica A., Xie, Xuping, Aguilar, Patricia, Weaver, Scott C., Shi, Pei-Yong, Walker, David H., Routh, Andrew L., Plante, Kenneth S., Menachery, Vineet D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8528077/ https://www.ncbi.nlm.nih.gov/pubmed/34671771 http://dx.doi.org/10.1101/2021.10.14.464390 |
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