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Targeting Aryl Hydrocarbon Receptor Signaling Enhances Type I Interferon-Independent Resistance to Herpes Simplex Virus

The aryl hydrocarbon receptor (AHR) is a ligand-activated transcript factor that plays an important role in regulating immunity and cell differentiation. However, its role in cell-autonomous antiviral resistance has not been fully elucidated. Here, we show that interruption of AHR signaling in human...

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Detalles Bibliográficos
Autores principales: Chen, Jincheng, Liang, Juan, Xu, Hui, Liu, Wenqi, Liu, Shuyan, Duan, Lian, Li, Fang, Wang, Zhaoqin, Liu, Yingxia, McSharry, Brian, Feng, Carl G., Zhang, Guoliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8528105/
https://www.ncbi.nlm.nih.gov/pubmed/34668726
http://dx.doi.org/10.1128/Spectrum.00473-21