N-Aryl mercaptoacetamides as potential multi-target inhibitors of metallo-β-lactamases (MBLs) and the virulence factor LasB from Pseudomonas aeruginosa

Increasing antimicrobial resistance is evolving to be one of the major threats to public health. To reduce the selection pressure and thus to avoid a fast development of resistance, novel approaches aim to target bacterial virulence instead of growth. Another strategy is to restore the activity of a...

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Detalles Bibliográficos
Autores principales: Yahiaoui, Samir, Voos, Katrin, Haupenthal, Jörg, Wichelhaus, Thomas A., Frank, Denia, Weizel, Lilia, Rotter, Marco, Brunst, Steffen, Kramer, Jan S., Proschak, Ewgenij, Ducho, Christian, Hirsch, Anna K. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8528214/
https://www.ncbi.nlm.nih.gov/pubmed/34778771
http://dx.doi.org/10.1039/d1md00187f

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