Enhanced Clostridioides difficile Infection Prevention With a Pharmacy-Controlled Policy That Adds a 3-Strain Lactobacillus Probiotic Concomitantly to Antibiotic Therapy

When 70% of antibiotic users took a 3-strain Lactobacillus probiotic preparation the hospital-wide rate of healthcare-associated Clostridioides difficile infection improved significantly. The incidence of C. difficile infection for those taking the probiotic along with multiple antibiotics or a sing...

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Autores principales: Maziade, Pierre-Jean, Ship, Noam, Sniffen, Jason C, Goldstein, Ellie J C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8528394/
https://www.ncbi.nlm.nih.gov/pubmed/33966076
http://dx.doi.org/10.1093/cid/ciab414
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author Maziade, Pierre-Jean
Ship, Noam
Sniffen, Jason C
Goldstein, Ellie J C
author_facet Maziade, Pierre-Jean
Ship, Noam
Sniffen, Jason C
Goldstein, Ellie J C
author_sort Maziade, Pierre-Jean
collection PubMed
description When 70% of antibiotic users took a 3-strain Lactobacillus probiotic preparation the hospital-wide rate of healthcare-associated Clostridioides difficile infection improved significantly. The incidence of C. difficile infection for those taking the probiotic along with multiple antibiotics or a single high-risk antibiotic was decreased by at least half.
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spelling pubmed-85283942021-10-21 Enhanced Clostridioides difficile Infection Prevention With a Pharmacy-Controlled Policy That Adds a 3-Strain Lactobacillus Probiotic Concomitantly to Antibiotic Therapy Maziade, Pierre-Jean Ship, Noam Sniffen, Jason C Goldstein, Ellie J C Clin Infect Dis Brief Reports When 70% of antibiotic users took a 3-strain Lactobacillus probiotic preparation the hospital-wide rate of healthcare-associated Clostridioides difficile infection improved significantly. The incidence of C. difficile infection for those taking the probiotic along with multiple antibiotics or a single high-risk antibiotic was decreased by at least half. Oxford University Press 2021-05-09 /pmc/articles/PMC8528394/ /pubmed/33966076 http://dx.doi.org/10.1093/cid/ciab414 Text en © The Author(s) 2021. Published by Oxford University Press for the Infectious Diseases Society of America. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (https://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Brief Reports
Maziade, Pierre-Jean
Ship, Noam
Sniffen, Jason C
Goldstein, Ellie J C
Enhanced Clostridioides difficile Infection Prevention With a Pharmacy-Controlled Policy That Adds a 3-Strain Lactobacillus Probiotic Concomitantly to Antibiotic Therapy
title Enhanced Clostridioides difficile Infection Prevention With a Pharmacy-Controlled Policy That Adds a 3-Strain Lactobacillus Probiotic Concomitantly to Antibiotic Therapy
title_full Enhanced Clostridioides difficile Infection Prevention With a Pharmacy-Controlled Policy That Adds a 3-Strain Lactobacillus Probiotic Concomitantly to Antibiotic Therapy
title_fullStr Enhanced Clostridioides difficile Infection Prevention With a Pharmacy-Controlled Policy That Adds a 3-Strain Lactobacillus Probiotic Concomitantly to Antibiotic Therapy
title_full_unstemmed Enhanced Clostridioides difficile Infection Prevention With a Pharmacy-Controlled Policy That Adds a 3-Strain Lactobacillus Probiotic Concomitantly to Antibiotic Therapy
title_short Enhanced Clostridioides difficile Infection Prevention With a Pharmacy-Controlled Policy That Adds a 3-Strain Lactobacillus Probiotic Concomitantly to Antibiotic Therapy
title_sort enhanced clostridioides difficile infection prevention with a pharmacy-controlled policy that adds a 3-strain lactobacillus probiotic concomitantly to antibiotic therapy
topic Brief Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8528394/
https://www.ncbi.nlm.nih.gov/pubmed/33966076
http://dx.doi.org/10.1093/cid/ciab414
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