Safety and efficacy of dimethyl fumarate in ALS: randomised controlled study

OBJECTIVE: Neuroinflammation is an important pathogenic mechanism in amyotrophic lateral sclerosis (ALS), with regulatory T cells (Tregs) mediating a slower rate of disease progression. Dimethyl fumarate enhances Treg levels and suppresses pro‐inflammatory T cells. The present study assessed the saf...

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Detalles Bibliográficos
Autores principales: Vucic, Steve, Henderson, Robert D., Mathers, Susan, Needham, Merrilee, Schultz, David, Kiernan, Matthew C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8528453/
https://www.ncbi.nlm.nih.gov/pubmed/34477330
http://dx.doi.org/10.1002/acn3.51446

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8528453/
https://www.ncbi.nlm.nih.gov/pubmed/34477330
http://dx.doi.org/10.1002/acn3.51446

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