Cargando…

Opinion on the impact of non‐monotonic dose responses on EFSA′s human health risk assessments

This Opinion assesses the biological relevance of the non‐monotonic dose responses (NMDR) identified in a previous EFSA External Report (Beausoleil et al., 2016) produced under GP/EFSA/SCER/2014/01 and the follow‐up probabilistic assessment (Chevillotte et al., 2017a,b), focusing on the in vivo data...

Descripción completa

Detalles Bibliográficos
Autores principales:	More, Simon, Benford, Diane, Hougaard Bennekou, Susanne, Bampidis, Vasileios, Bragard, Claude, Halldorsson, Thorhallur, Hernandez‐Jerez, Antonio, Koutsoumanis, Kostas, Lambré, Claude, Machera, Kyriaki, Mullins, Ewen, Nielsen, Søren Saxmose, Schlatter, Josef, Schrenk, Dieter, Turck, Dominique, Tarazona, Jose, Younes, Maged
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Scientific Opinion
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8528485/ https://www.ncbi.nlm.nih.gov/pubmed/34712366 http://dx.doi.org/10.2903/j.efsa.2021.6877

Ejemplares similares

Guidance on protocol development for EFSA generic scientific assessments
por: More, Simon, et al.
Publicado: (2023)

Draft for internal testing Scientific Committee guidance on appraising and integrating evidence from epidemiological studies for use in EFSA's scientific assessments
por: More, Simon, et al.
Publicado: (2020)

Evaluation of existing guidelines for their adequacy for the food and feed risk assessment of microorganisms obtained through synthetic biology
por: More, Simon, et al.
Publicado: (2022)

Guidance on the use of the benchmark dose approach in risk assessment
por: More, Simon John, et al.
Publicado: (2022)

Statement on the derivation of Health‐Based Guidance Values (HBGVs) for regulated products that are also nutrients
por: More, Simon, et al.
Publicado: (2021)

Evaluation of existing guidelines for their adequacy for the microbial characterisation and environmental risk assessment of microorganisms obtained through synthetic biology
por: More, Simon, et al.
Publicado: (2020)

Guidance Document on Scientific criteria for grouping chemicals into assessment groups for human risk assessment of combined exposure to multiple chemicals
por: More, Simon John, et al.
Publicado: (2021)

A systems‐based approach to the environmental risk assessment of multiple stressors in honey bees
por: More, Simon, et al.
Publicado: (2021)

Guidance on aneugenicity assessment
por: More, Simon John, et al.
Publicado: (2021)

Re‐evaluation of the existing health‐based guidance values for copper and exposure assessment from all sources
por: More, Simon John, et al.
Publicado: (2023)

Guidance on technical requirements for regulated food and feed product applications to establish the presence of small particles including nanoparticles
por: More, Simon, et al.
Publicado: (2021)

Guidance on risk assessment of nanomaterials to be applied in the food and feed chain: human and animal health
por: More, Simon, et al.
Publicado: (2021)

Guidance on the use of the Threshold of Toxicological Concern approach in food safety assessment
por: More, Simon J, et al.
Publicado: (2019)

Genotoxicity assessment of chemical mixtures
por: More, Simon, et al.
Publicado: (2018)

Scientific motivations and criteria to consider updating EFSA scientific assessments
por: Hardy, Anthony, et al.
Publicado: (2017)

The principles and methods behind EFSA's Guidance on Uncertainty Analysis in Scientific Assessment
por: Benford, Diane, et al.
Publicado: (2018)

Guidance on harmonised methodologies for human health, animal health and ecological risk assessment of combined exposure to multiple chemicals
por: More, Simon John, et al.
Publicado: (2019)

Guidance on Uncertainty Analysis in Scientific Assessments
por: Benford, Diane, et al.
Publicado: (2018)

Use of EFSA Pesticide Residue Intake Model (EFSA PRIMo revision 3)
por: Brancato, Alba, et al.
Publicado: (2018)

Guidance on risk assessment of the application of nanoscience and nanotechnologies in the food and feed chain: Part 1, human and animal health
por: Hardy, Anthony, et al.
Publicado: (2018)

Guidance on dermal absorption
por: Buist, Harrie, et al.
Publicado: (2017)

Monotone and near-monotone biochemical networks
por: Sontag, Eduardo D.
Publicado: (2007)

EFSA is working to protect bees and shape the future of environmental risk assessment
por: More, Simon J, et al.
Publicado: (2021)

Guidance on the risk assessment of substances present in food intended for infants below 16 weeks of age
por: Hardy, Anthony, et al.
Publicado: (2017)

Clarification of some aspects related to genotoxicity assessment
por: Hardy, Anthony, et al.
Publicado: (2017)

Minimax and monotonicity
por: Simons, Stephen
Publicado: (1998)

Monotonous Diet
Publicado: (1890)

Editorial: The future of data in EFSA
por: Cappè, Stefano, et al.
Publicado: (2019)

Update of the list of QPS‐recommended biological agents intentionally added to food or feed as notified to EFSA 9: suitability of taxonomic units notified to EFSA until September 2018
por: Koutsoumanis, Kostas, et al.
Publicado: (2019)

Ordered, Random, Monotonic and Non-Monotonic Digital Nanodot Gradients
por: Ongo, Grant, et al.
Publicado: (2014)

Update of the list of QPS‐recommended biological agents intentionally added to food or feed as notified to EFSA 12: suitability of taxonomic units notified to EFSA until March 2020
por: Koutsoumanis, Kostas, et al.
Publicado: (2020)

Update of the list of QPS‐recommended biological agents intentionally added to food or feed as notified to EFSA 11: suitability of taxonomic units notified to EFSA until September 2019
por: Koutsoumanis, Kostas, et al.
Publicado: (2020)

Update of the list of QPS‐recommended biological agents intentionally added to food or feed as notified to EFSA 10: Suitability of taxonomic units notified to EFSA until March 2019
por: Koutsoumanis, Kostas, et al.
Publicado: (2019)

Update of the list of QPS‐recommended biological agents intentionally added to food or feed as notified to EFSA 15: suitability of taxonomic units notified to EFSA until September 2021
por: Koutsoumanis, Kostas, et al.
Publicado: (2022)

Update of the list of QPS‐recommended biological agents intentionally added to food or feed as notified to EFSA 14: suitability of taxonomic units notified to EFSA until March 2021
por: Koutsoumanis, Kostas, et al.
Publicado: (2021)

Update of the list of QPS‐recommended biological agents intentionally added to food or feed as notified to EFSA 13: suitability of taxonomic units notified to EFSA until September 2020
por: Koutsoumanis, Kostas, et al.
Publicado: (2021)

Moving towards a holistic approach for human health risk assessment – Is the current approach fit for purpose?
por: Bennekou, Susanne Hougaard
Publicado: (2019)

Guidance on the use of the weight of evidence approach in scientific assessments
por: Hardy, Anthony, et al.
Publicado: (2017)

Update of the list of QPS‐recommended biological agents intentionally added to food or feed as notified to EFSA 7: suitability of taxonomic units notified to EFSA until September 2017
por: Ricci, Antonia, et al.
Publicado: (2018)

Update of the list of QPS‐recommended biological agents intentionally added to food or feed as notified to EFSA 5: suitability of taxonomic units notified to EFSA until September 2016
por: Ricci, Antonia, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_ag3i0u5l03201gjf0l2rgj9v0k