Cargando…

Cetuximab-Modified Human Serum Albumin Nanoparticles Co-Loaded with Doxorubicin and MDR1 siRNA for the Treatment of Drug-Resistant Breast Tumors

BACKGROUND: Breast cancer is the most prevalent cancer among women. Doxorubicin (DOX) is a common chemotherapeutic drug used to treat many different cancers. However, multidrug resistance limits the treatment of breast cancer. MDR1 siRNA (siMDR1) combinatorial therapy has attracted significant atten...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Xin, Wang, Yifan, Chen, Si, Zhang, Shuang, Cui, Chunying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8528549/ https://www.ncbi.nlm.nih.gov/pubmed/34703227 http://dx.doi.org/10.2147/IJN.S332830

Ejemplares similares

Preparation Optimization of Bovine Serum Albumin Nanoparticles and Its Application for siRNA Delivery
por: Wang, Yifan, et al.
Publicado: (2021)

Inhibition of MDR1 expression with altritol-modified siRNAs
por: Fisher, Michael, et al.
Publicado: (2007)

Codelivery of doxorubicin and MDR1-siRNA by mesoporous silica nanoparticles-polymerpolyethylenimine to improve oral squamous carcinoma treatment
por: Wang, Dandan, et al.
Publicado: (2017)

EGFR Targeted Cetuximab-Valine-Citrulline (vc)-Doxorubicin Immunoconjugates- Loaded Bovine Serum Albumin (BSA) Nanoparticles for Colorectal Tumor Therapy
por: Ye, Zixuan, et al.
Publicado: (2021)

Codelivery of Doxorubicin and MDR1-siRNA by Mesoporous Silica Nanoparticles-Polymerpolyethylenimine to Improve Oral Squamous Carcinoma Treatment [Corrigendum]
Publicado: (2021)

Multifunctional nanoparticles co-loaded with Adriamycin and MDR-targeting siRNAs for treatment of chemotherapy-resistant esophageal cancer
por: Zhang, Xiangyang, et al.
Publicado: (2022)

Doxorubicin and anti-VEGF siRNA co-delivery via nano-graphene oxide for enhanced cancer therapy in vitro and in vivo
por: Sun, Qi, et al.
Publicado: (2018)

Albumin pre-coating enhances intracellular siRNA delivery of multifunctional amphiphile/siRNA nanoparticles
por: Kummitha, China M, et al.
Publicado: (2012)

Anti-EpCAM functionalized graphene oxide vector for tumor targeted siRNA delivery and cancer therapy
por: Chen, Si, et al.
Publicado: (2021)

Synergistic treatment of osteosarcoma with biomimetic nanoparticles transporting doxorubicin and siRNA
por: Zhao, Jingtong, et al.
Publicado: (2023)

Doxorubicin-conjugated siRNA lipid nanoparticles for combination cancer therapy
por: Butowska, Kamila, et al.
Publicado: (2023)

Calcium-siRNA Nanocomplexes Optimized by Bovine Serum Albumin Coating Can Achieve Convenient and Efficient siRNA Delivery for Periodontitis Therapy
por: Wang, Yang, et al.
Publicado: (2020)

Preparation and Characterization of Functionalized Graphene Oxide Carrier for siRNA Delivery
por: Li, Jing, et al.
Publicado: (2018)

Nanolipoparticles-mediated MDR1 siRNA delivery reduces doxorubicin resistance in breast cancer cells and silences MDR1 expression in xenograft model of human breast cancer
por: Nourbakhsh, Mahnaz, et al.
Publicado: (2015)

MDR1 siRNA loaded hyaluronic acid-based CD44 targeted nanoparticle systems circumvent paclitaxel resistance in ovarian cancer
por: Yang, Xiaoqian, et al.
Publicado: (2015)

siRNA-loaded selenium nanoparticle modified with hyaluronic acid for enhanced hepatocellular carcinoma therapy
por: Xia, Yu, et al.
Publicado: (2018)

Dual Targeted Nanoparticles for the Codelivery of Doxorubicin and siRNA Cocktails to Overcome Ovarian Cancer Stem Cells
por: Chen, Li, et al.
Publicado: (2023)

Design, synthesis and evaluation of VEGF-siRNA/CRS as a novel vector for gene delivery
por: Zhao, Wen, et al.
Publicado: (2016)

The siRNA targeted to mdr1b and mdr1a mRNAs in vivo sensitizes murine lymphosarcoma to chemotherapy
por: Patutina, Olga A, et al.
Publicado: (2010)

Characterization of modified mesoporous silica nanoparticles as vectors for siRNA delivery
por: Slita, Anna, et al.
Publicado: (2018)

Enzyme-triggered PEGylated siRNA-nanoparticles for controlled release of siRNA
por: Yingyuad, Peerada, et al.
Publicado: (2014)

Lipid-coated albumin-paclitaxel nanoparticles loaded with sorcin-siRNA reverse cancer chemoresistance via restoring intracellular calcium ion homeostasis
por: Wang, Chenglong, et al.
Publicado: (2022)

Novel functionalized nanoparticles for tumor-targeting co-delivery of doxorubicin and siRNA to enhance cancer therapy
por: Xia, Yu, et al.
Publicado: (2017)

Redox/pH-Responsive 2-in-1 Chimeric Nanoparticles for the Co-Delivery of Doxorubicin and siRNA
por: Wu, Hsi-Chin, et al.
Publicado: (2021)

Doxorubicin-loaded human serum albumin nanoparticles overcome transporter-mediated drug resistance in drug-adapted cancer cells
por: Onafuye, Hannah, et al.
Publicado: (2019)

Enhanced Gene Silencing through Human Serum Albumin-Mediated Delivery of Polyethylenimine-siRNA Polyplexes
por: Nicolì, Elena, et al.
Publicado: (2015)

Combination of polythyleneimine regulating autophagy prodrug and Mdr1 siRNA for tumor multidrug resistance
por: Wang, Changduo, et al.
Publicado: (2022)

Silver Nanoparticles Surface-Modified with Carbosilane Dendrons as Carriers of Anticancer siRNA
por: Pędziwiatr-Werbicka, Elżbieta, et al.
Publicado: (2020)

Glycol chitosan nanoparticles as specialized cancer therapeutic vehicles: Sequential delivery of doxorubicin and Bcl-2 siRNA
por: Yoon, Hong Yeol, et al.
Publicado: (2014)

Liver-Targeted Combination Therapy Basing on Glycyrrhizic Acid-Modified DSPE-PEG-PEI Nanoparticles for Co-delivery of Doxorubicin and Bcl-2 siRNA
por: Tian, Guixiang, et al.
Publicado: (2019)

Substance P-modified human serum albumin nanoparticles loaded with paclitaxel for targeted therapy of glioma
por: Ruan, Chunhui, et al.
Publicado: (2018)

Cell-Penetrating Peptide-Modified Graphene Oxide Nanoparticles Loaded with Rictor siRNA for the Treatment of Triple-Negative Breast Cancer
por: Yang, Yun-Yun, et al.
Publicado: (2021)

Novel targeted siRNA-loaded hybrid nanoparticles: preparation, characterization and in vitro evaluation
por: Dim, Nneka, et al.
Publicado: (2015)

Local delivery of siRNA-loaded calcium phosphate nanoparticles abates pulmonary inflammation
por: Frede, Annika, et al.
Publicado: (2017)

Effective Delivery of siRNA-Loaded Nanoparticles for Overcoming Oxaliplatin Resistance in Colorectal Cancer
por: Zhou, Yue, et al.
Publicado: (2022)

Effect of Cationic Lipid Nanoparticle Loaded siRNA with Stearylamine against Chikungunya Virus
por: Jeengar, Manish Kumar, et al.
Publicado: (2022)

Protection and Systemic Translocation of siRNA Following Oral Administration of Chitosan/siRNA Nanoparticles
por: Ballarín-González, Borja, et al.
Publicado: (2013)

Anti-HER2 functionalized graphene oxide as survivin-siRNA delivery carrier inhibits breast carcinoma growth in vitro and in vivo
por: Wang, Xiaoli, et al.
Publicado: (2018)

Doxorubicin combined with Notch1-targeting siRNA for the treatment of gastric cancer
por: Zhou, Wei, et al.
Publicado: (2018)

Conjugation of Doxorubicin to siRNA Through Disulfide-based Self-immolative Linkers
por: Gauthier, Florian, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_fkh0ehtruugfv5i6fegev0kmqq