Cargando…

Regression Analysis of Factors Based on Cluster Analysis of Acute Radiation Pneumonia due to Radiation Therapy for Lung Cancer

We conducted in this paper a regression analysis of factors associated with acute radiation pneumonia due to radiation therapy for lung cancer utilizing cluster analysis to explore the predictive effects of clinical and dosimetry factors on grade ≥2 radiation pneumonia due to radiation therapy for l...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Xiaofeng, Lv, Beili, Rui, Lijun, Cai, Liming, Liu, Fenglan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8528627/
https://www.ncbi.nlm.nih.gov/pubmed/34691377
http://dx.doi.org/10.1155/2021/3727794
_version_ 1784586288782901248
author Zhang, Xiaofeng
Lv, Beili
Rui, Lijun
Cai, Liming
Liu, Fenglan
author_facet Zhang, Xiaofeng
Lv, Beili
Rui, Lijun
Cai, Liming
Liu, Fenglan
author_sort Zhang, Xiaofeng
collection PubMed
description We conducted in this paper a regression analysis of factors associated with acute radiation pneumonia due to radiation therapy for lung cancer utilizing cluster analysis to explore the predictive effects of clinical and dosimetry factors on grade ≥2 radiation pneumonia due to radiation therapy for lung cancer and to further refine the effect of the ratio of the volume of the primary foci to the volume of the lung lobes in which they are located on radiation pneumonia, to refine the factors that are clinically effective in predicting the occurrence of grade ≥2 radiation pneumonia. This will provide a basis for better guiding lung cancer radiation therapy, reducing the occurrence of grade ≥2 radiation pneumonia, and improving the safety of radiotherapy. Based on the characteristics of the selected surveillance data, the experimental simulation of the factors of acute radiation pneumonia due to lung cancer radiation therapy was performed based on three signal detection methods using fuzzy mean clustering algorithm with drug names as the target and adverse drug reactions as the characteristics, and the drugs were classified into three categories. The method was then designed and used to determine the classification correctness evaluation function as the best signal detection method. The factor classification and risk feature identification of acute radiation pneumonia due to radiation therapy for lung cancer based on ADR were achieved by using cluster analysis and feature extraction techniques, which provided a referenceable method for establishing the factor classification mechanism of acute radiation pneumonia due to radiation therapy for lung cancer and a new idea for reuse of ADR surveillance report data resources.
format Online
Article
Text
id pubmed-8528627
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Hindawi
record_format MEDLINE/PubMed
spelling pubmed-85286272021-10-21 Regression Analysis of Factors Based on Cluster Analysis of Acute Radiation Pneumonia due to Radiation Therapy for Lung Cancer Zhang, Xiaofeng Lv, Beili Rui, Lijun Cai, Liming Liu, Fenglan J Healthc Eng Research Article We conducted in this paper a regression analysis of factors associated with acute radiation pneumonia due to radiation therapy for lung cancer utilizing cluster analysis to explore the predictive effects of clinical and dosimetry factors on grade ≥2 radiation pneumonia due to radiation therapy for lung cancer and to further refine the effect of the ratio of the volume of the primary foci to the volume of the lung lobes in which they are located on radiation pneumonia, to refine the factors that are clinically effective in predicting the occurrence of grade ≥2 radiation pneumonia. This will provide a basis for better guiding lung cancer radiation therapy, reducing the occurrence of grade ≥2 radiation pneumonia, and improving the safety of radiotherapy. Based on the characteristics of the selected surveillance data, the experimental simulation of the factors of acute radiation pneumonia due to lung cancer radiation therapy was performed based on three signal detection methods using fuzzy mean clustering algorithm with drug names as the target and adverse drug reactions as the characteristics, and the drugs were classified into three categories. The method was then designed and used to determine the classification correctness evaluation function as the best signal detection method. The factor classification and risk feature identification of acute radiation pneumonia due to radiation therapy for lung cancer based on ADR were achieved by using cluster analysis and feature extraction techniques, which provided a referenceable method for establishing the factor classification mechanism of acute radiation pneumonia due to radiation therapy for lung cancer and a new idea for reuse of ADR surveillance report data resources. Hindawi 2021-10-13 /pmc/articles/PMC8528627/ /pubmed/34691377 http://dx.doi.org/10.1155/2021/3727794 Text en Copyright © 2021 Xiaofeng Zhang et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Zhang, Xiaofeng
Lv, Beili
Rui, Lijun
Cai, Liming
Liu, Fenglan
Regression Analysis of Factors Based on Cluster Analysis of Acute Radiation Pneumonia due to Radiation Therapy for Lung Cancer
title Regression Analysis of Factors Based on Cluster Analysis of Acute Radiation Pneumonia due to Radiation Therapy for Lung Cancer
title_full Regression Analysis of Factors Based on Cluster Analysis of Acute Radiation Pneumonia due to Radiation Therapy for Lung Cancer
title_fullStr Regression Analysis of Factors Based on Cluster Analysis of Acute Radiation Pneumonia due to Radiation Therapy for Lung Cancer
title_full_unstemmed Regression Analysis of Factors Based on Cluster Analysis of Acute Radiation Pneumonia due to Radiation Therapy for Lung Cancer
title_short Regression Analysis of Factors Based on Cluster Analysis of Acute Radiation Pneumonia due to Radiation Therapy for Lung Cancer
title_sort regression analysis of factors based on cluster analysis of acute radiation pneumonia due to radiation therapy for lung cancer
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8528627/
https://www.ncbi.nlm.nih.gov/pubmed/34691377
http://dx.doi.org/10.1155/2021/3727794
work_keys_str_mv AT zhangxiaofeng regressionanalysisoffactorsbasedonclusteranalysisofacuteradiationpneumoniaduetoradiationtherapyforlungcancer
AT lvbeili regressionanalysisoffactorsbasedonclusteranalysisofacuteradiationpneumoniaduetoradiationtherapyforlungcancer
AT ruilijun regressionanalysisoffactorsbasedonclusteranalysisofacuteradiationpneumoniaduetoradiationtherapyforlungcancer
AT cailiming regressionanalysisoffactorsbasedonclusteranalysisofacuteradiationpneumoniaduetoradiationtherapyforlungcancer
AT liufenglan regressionanalysisoffactorsbasedonclusteranalysisofacuteradiationpneumoniaduetoradiationtherapyforlungcancer