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Primary Head and Neck Tumour-Derived Fibroblasts Promote Lymphangiogenesis in a Lymphatic Organotypic Co-culture Model
BACKGROUND: In head and neck cancer, intratumour lymphatic density and tumour lymphangiogenesis have been correlated with lymphatic metastasis, making lymphangiogenesis a promising therapeutic target. However, inter-patient tumour heterogeneity makes it challenging to predict tumour progression and...
Autores principales: | Lugo-Cintrón, Karina M., Ayuso, José M., Humayun, Mouhita, Gong, Max M., Kerr, Sheena C., Ponik, Suzanne M., Harari, Paul M., Virumbrales-Muñoz, María, Beebe, David J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8528684/ https://www.ncbi.nlm.nih.gov/pubmed/34673450 http://dx.doi.org/10.1016/j.ebiom.2021.103634 |
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