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Human cerebral vascular amyloid contains both antiparallel and parallel in-register Aβ40 fibrils

The accumulation of fibrillar amyloid-β (Aβ) peptides alongside or within the cerebral vasculature is the hallmark of cerebral amyloid angiopathy (CAA). This condition commonly co-occurs with Alzheimer's disease (AD) and leads to cerebral microbleeds, intracranial hemorrhages, and stroke. CAA a...

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Detalles Bibliográficos
Autores principales:	Irizarry, Brandon A., Davis, Judianne, Zhu, Xiaoyue, Boon, Baayla D.C., Rozemuller, Annemieke J.M., Van Nostrand, William E., Smith, Steven O.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8528725/ https://www.ncbi.nlm.nih.gov/pubmed/34599967 http://dx.doi.org/10.1016/j.jbc.2021.101259

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