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Anthracycline-free tumor elimination in mice leads to functional and molecular cardiac recovery from cancer-induced alterations in contrast to long-lasting doxorubicin treatment effects

Systemic effects of advanced cancer impact on the heart leading to cardiac atrophy and functional impairment. Using a murine melanoma cancer model (B16F10 melanoma cells stably transduced with a Ganciclovir (GCV)-inducible suicide gene), the present study analysed the recovery potential of cancer-in...

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Detalles Bibliográficos
Autores principales: Pietzsch, Stefan, Wohlan, Katharina, Thackeray, James T., Heimerl, Maren, Schuchardt, Sven, Scherr, Michaela, Ricke-Hoch, Melanie, Hilfiker-Kleiner, Denise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8528750/
https://www.ncbi.nlm.nih.gov/pubmed/34669013
http://dx.doi.org/10.1007/s00395-021-00902-7