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Mice lacking DYRK2 exhibit congenital malformations with lung hypoplasia and altered Foxf1 expression gradient

Congenital malformations cause life-threatening diseases in pediatrics, yet the molecular mechanism of organogenesis is poorly understood. Here we show that Dyrk2-deficient mice display congenital malformations in multiple organs. Transcriptome analysis reveals molecular pathology of Dyrk2-deficient...

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Detalles Bibliográficos
Autores principales:	Yogosawa, Satomi, Ohkido, Makiko, Horii, Takuro, Okazaki, Yasumasa, Nakayama, Jun, Yoshida, Saishu, Toyokuni, Shinya, Hatada, Izuho, Morimoto, Mitsuru, Yoshida, Kiyotsugu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8528819/ https://www.ncbi.nlm.nih.gov/pubmed/34671097 http://dx.doi.org/10.1038/s42003-021-02734-6

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