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Bayesian log-normal deconvolution for enhanced in silico microdissection of bulk gene expression data

Deconvolution of bulk gene expression profiles into the cellular components is pivotal to portraying tissue’s complex cellular make-up, such as the tumor microenvironment. However, the inherently variable nature of gene expression requires a comprehensive statistical model and reliable prior knowled...

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Detalles Bibliográficos
Autores principales:	Andrade Barbosa, Bárbara, van Asten, Saskia D., Oh, Ji Won, Farina-Sarasqueta, Arantza, Verheij, Joanne, Dijk, Frederike, van Laarhoven, Hanneke W. M., Ylstra, Bauke, Garcia Vallejo, Juan J., van de Wiel, Mark A., Kim, Yongsoo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8528834/ https://www.ncbi.nlm.nih.gov/pubmed/34671028 http://dx.doi.org/10.1038/s41467-021-26328-2

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