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An alphavirus replicon-based vaccine expressing a stabilized Spike antigen induces protective immunity and prevents transmission of SARS-CoV-2 between cats
Early in the SARS-CoV-2 pandemic concerns were raised regarding infection of new animal hosts and the effect on viral epidemiology. Infection of other animals could be detrimental by causing clinical disease, allowing further mutations, and bares the risk for the establishment of a non-human reservo...
Autores principales: | Langereis, Martijn A., Albulescu, Irina C., Stammen-Vogelzangs, Judith, Lambregts, Morindy, Stachura, Ken, Miller, Suzan, Bosco-Lauth, Angela M., Hartwig, Airn E., Porter, Stephanie M., Allen, Michelle, Mogler, Mark, van Kuppeveld, Frank J. M., Bosch, Berend-Jan, Vermeij, Paul, de Groof, Ad, Bowen, Richard A., Davis, Randy, Xu, Zach, Tarpey, Ian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8528862/ https://www.ncbi.nlm.nih.gov/pubmed/34671047 http://dx.doi.org/10.1038/s41541-021-00390-9 |
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