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GOLPH3/CKAP4 promotes metastasis and tumorigenicity by enhancing the secretion of exosomal WNT3A in non-small-cell lung cancer

Cancer metastasis is the main cause of mortality associated with non-small-cell lung cancer (NSCLC), accounting for up to 70% of deaths among patients. The mechanisms underlying distal metastasis remain largely unknown. Golgi phosphoprotein 3 (GOLPH3) correlates negatively with overall survival in m...

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Detalles Bibliográficos
Autores principales: Song, Jun-Wei, Zhu, Jing, Wu, Xing-Xuan, Tu, Ting, Huang, Jing-Qiang, Chen, Guan-Zi, Liang, Li-Yin, Zhou, Chun-Hui, Xu, XingZhi, Gong, Li-Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8528870/
https://www.ncbi.nlm.nih.gov/pubmed/34671013
http://dx.doi.org/10.1038/s41419-021-04265-8