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Tumor-suppressive function of EZH2 is through inhibiting glutaminase

Tumors can use metabolic reprogramming to survive nutrient stress. Epigenetic regulators play a critical role in metabolic adaptation. Here we screened a sgRNA library to identify epigenetic regulators responsible for the vulnerability of colorectal cancer (CRC) cells to glucose deprivation and foun...

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Detalles Bibliográficos
Autores principales:	Liu, Yongfeng, Tu, Cheng-e, Guo, Xuxue, Wu, Changjie, Gu, Chuncai, Lai, Qiuhua, Fang, Yuxin, Huang, Junqi, Wang, Zhizhang, Li, Aimin, Liu, Side
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8528894/ https://www.ncbi.nlm.nih.gov/pubmed/34671029 http://dx.doi.org/10.1038/s41419-021-04212-7

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