Bilobalide inhibits inflammation and promotes the expression of Aβ degrading enzymes in astrocytes to rescue neuronal deficiency in AD models

The pathogenesis of Alzheimer’s disease (AD) involves multiple cell types including endothelial cells, glia, and neurons. It suggests that therapy against single target in single cell type may not be sufficient to treat AD and therapies with protective effects in multiple cell types may be more effe...

Descripción completa

Detalles Bibliográficos
Autores principales: Xiang, Jun, Yang, Feng, Zhu, Wen, Cai, Min, Li, Xiang-Ting, Zhang, Jing-Si, Yu, Zhong-Hai, Zhang, Wen, Cai, Ding-Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8528910/
https://www.ncbi.nlm.nih.gov/pubmed/34671017
http://dx.doi.org/10.1038/s41398-021-01594-2

Ejemplares similares

Ejemplares similares