GAK and PRKCD are positive regulators of PRKN-independent mitophagy

The mechanisms involved in programmed or damage-induced removal of mitochondria by mitophagy remains elusive. Here, we have screened for regulators of PRKN-independent mitophagy using an siRNA library targeting 197 proteins containing lipid interacting domains. We identify Cyclin G-associated kinase...

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Detalles Bibliográficos
Autores principales: Munson, Michael J., Mathai, Benan J., Ng, Matthew Yoke Wui, Trachsel-Moncho, Laura, de la Ballina, Laura R., Schultz, Sebastian W., Aman, Yahyah, Lystad, Alf H., Singh, Sakshi, Singh, Sachin, Wesche, Jørgen, Fang, Evandro F., Simonsen, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8528926/
https://www.ncbi.nlm.nih.gov/pubmed/34671015
http://dx.doi.org/10.1038/s41467-021-26331-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8528926/
https://www.ncbi.nlm.nih.gov/pubmed/34671015
http://dx.doi.org/10.1038/s41467-021-26331-7

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