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Discovery and characterization of high-affinity, potent SARS-CoV-2 neutralizing antibodies via single B cell screening

Monoclonal antibodies that target SARS-CoV-2 with high affinity are valuable for a wide range of biomedical applications involving novel coronavirus disease (COVID-19) diagnosis, treatment, and prophylactic intervention. Strategies for the rapid and reliable isolation of these antibodies, especially...

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Detalles Bibliográficos
Autores principales: Schardt, John S., Pornnoppadol, Ghasidit, Desai, Alec A., Park, Kyung Soo, Zupancic, Jennifer M., Makowski, Emily K., Smith, Matthew D., Chen, Hongwei, Garcia de Mattos Barbosa, Mayara, Cascalho, Marilia, Lanigan, Thomas M., Moon, James J., Tessier, Peter M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8528929/
https://www.ncbi.nlm.nih.gov/pubmed/34671080
http://dx.doi.org/10.1038/s41598-021-99401-x

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