Lung Allograft Epithelium DNA Methylation Age Is Associated With Graft Chronologic Age and Primary Graft Dysfunction

Advanced donor age is a risk factor for poor survival following lung transplantation. However, recent work identifying epigenetic determinants of aging has shown that biologic age may not always reflect chronologic age and that stressors can accelerate biologic aging. We hypothesized that lung allog...

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Detalles Bibliográficos
Autores principales: Dugger, Daniel T., Calabrese, Daniel R., Gao, Ying, Deiter, Fred, Tsao, Tasha, Maheshwari, Julia, Hays, Steven R., Leard, Lorriana, Kleinhenz, Mary Ellen, Shah, Rupal, Golden, Jeff, Kukreja, Jasleen, Gordon, Erin D., Singer, Jonathan P., Greenland, John R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8528961/
https://www.ncbi.nlm.nih.gov/pubmed/34691018
http://dx.doi.org/10.3389/fimmu.2021.704172

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