Evaluation of Natalizumab Pharmacokinetics and Pharmacodynamics: Toward Individualized Doses

Background: Plasma concentration of natalizumab falls above the therapeutic threshold in many patients who, therefore, receive more natalizumab than necessary and have higher risk of progressive multifocal leukoencephalopathy. Objective: To assess in a single study the individual and treatment chara...

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Detalles Bibliográficos
Autores principales: Serra López-Matencio, Jose M., Pérez García, Yaiza, Meca-Lallana, Virginia, Juárez-Sánchez, Raquel, Ursa, Angeles, Vega-Piris, Lorena, Pascual-Salcedo, Dora, de Vries, Annick, Rispens, Theo, Muñoz-Calleja, Cecilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Neurology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8529019/
https://www.ncbi.nlm.nih.gov/pubmed/34690914
http://dx.doi.org/10.3389/fneur.2021.716548

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