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Testing Fmr1(KO) Phenotypes in Response to GSK3 Inhibitors: SB216763 versus AFC03127
Glycogen synthase kinase 3 (GSK3) is a proline-directed serine-threonine kinase that is associated with several neurological disorders, including Alzheimer’s disease and fragile X syndrome (FXS). We tested the efficacy of a novel GSK3 inhibitor AFC03127, which was developed by Angelini Pharma, in co...
Autores principales: | Westmark, Pamela R., Garrone, Beatrice, Ombrato, Rosella, Milanese, Claudio, Di Giorgio, Francesco Paolo, Westmark, Cara J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8529056/ https://www.ncbi.nlm.nih.gov/pubmed/34690696 http://dx.doi.org/10.3389/fnmol.2021.751307 |
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