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The Role of Microbiota in Infant Health: From Early Life to Adulthood
From early life to adulthood, the microbiota play a crucial role in the health of the infant. The microbiota in early life are not only a key regulator of infant health but also associated with long-term health. Pregnancy to early life is the golden time for the establishment of the infant microbiot...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8529064/ https://www.ncbi.nlm.nih.gov/pubmed/34691021 http://dx.doi.org/10.3389/fimmu.2021.708472 |
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author | Yao, Yao Cai, Xiaoyu Ye, Yiqing Wang, Fengmei Chen, Fengying Zheng, Caihong |
author_facet | Yao, Yao Cai, Xiaoyu Ye, Yiqing Wang, Fengmei Chen, Fengying Zheng, Caihong |
author_sort | Yao, Yao |
collection | PubMed |
description | From early life to adulthood, the microbiota play a crucial role in the health of the infant. The microbiota in early life are not only a key regulator of infant health but also associated with long-term health. Pregnancy to early life is the golden time for the establishment of the infant microbiota, which is affected by both environmental and genetic factors. Recently, there is an explosion of the studies on the role of microbiota in human diseases, but the application to disease or health is relatively limited because many aspects of human microbiota remain controversial, especially about the infant microbiota. Therefore, a critical and conclusive review is necessary to understand fully the relationship between the microbiota and the health of infant. In this article, we introduce in detail the role of microbiota in the infant from pregnancy to early life to long-term health. The main contents of this article include the relationship between the maternal microbiota and adverse pregnancy outcomes, the establishment of the neonatal microbiota during perinatal period and early life, the composition of the infant gut microbiota, the prediction of the microbiota for long-term health, and the future study directions of microbiota. |
format | Online Article Text |
id | pubmed-8529064 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-85290642021-10-22 The Role of Microbiota in Infant Health: From Early Life to Adulthood Yao, Yao Cai, Xiaoyu Ye, Yiqing Wang, Fengmei Chen, Fengying Zheng, Caihong Front Immunol Immunology From early life to adulthood, the microbiota play a crucial role in the health of the infant. The microbiota in early life are not only a key regulator of infant health but also associated with long-term health. Pregnancy to early life is the golden time for the establishment of the infant microbiota, which is affected by both environmental and genetic factors. Recently, there is an explosion of the studies on the role of microbiota in human diseases, but the application to disease or health is relatively limited because many aspects of human microbiota remain controversial, especially about the infant microbiota. Therefore, a critical and conclusive review is necessary to understand fully the relationship between the microbiota and the health of infant. In this article, we introduce in detail the role of microbiota in the infant from pregnancy to early life to long-term health. The main contents of this article include the relationship between the maternal microbiota and adverse pregnancy outcomes, the establishment of the neonatal microbiota during perinatal period and early life, the composition of the infant gut microbiota, the prediction of the microbiota for long-term health, and the future study directions of microbiota. Frontiers Media S.A. 2021-10-07 /pmc/articles/PMC8529064/ /pubmed/34691021 http://dx.doi.org/10.3389/fimmu.2021.708472 Text en Copyright © 2021 Yao, Cai, Ye, Wang, Chen and Zheng https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Immunology Yao, Yao Cai, Xiaoyu Ye, Yiqing Wang, Fengmei Chen, Fengying Zheng, Caihong The Role of Microbiota in Infant Health: From Early Life to Adulthood |
title | The Role of Microbiota in Infant Health: From Early Life to Adulthood |
title_full | The Role of Microbiota in Infant Health: From Early Life to Adulthood |
title_fullStr | The Role of Microbiota in Infant Health: From Early Life to Adulthood |
title_full_unstemmed | The Role of Microbiota in Infant Health: From Early Life to Adulthood |
title_short | The Role of Microbiota in Infant Health: From Early Life to Adulthood |
title_sort | role of microbiota in infant health: from early life to adulthood |
topic | Immunology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8529064/ https://www.ncbi.nlm.nih.gov/pubmed/34691021 http://dx.doi.org/10.3389/fimmu.2021.708472 |
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