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Ironing out the distribution of [2Fe-2S] motifs in ferrochelatases

Heme, a near ubiquitous cofactor, is synthesized by most organisms. The essential step of insertion of iron into the porphyrin macrocycle is mediated by the enzyme ferrochelatase. Several ferrochelatases have been characterized, and it has been experimentally shown that a fraction of them contain [2...

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Detalles Bibliográficos
Autores principales: Weerth, R. Sophia, Medlock, Amy E., Dailey, Harry A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8529089/
https://www.ncbi.nlm.nih.gov/pubmed/34582890
http://dx.doi.org/10.1016/j.jbc.2021.101017