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NKG2D Engagement Alone Is Sufficient to Activate Cytokine-Induced Killer Cells While 2B4 Only Provides Limited Coactivation

Cytokine-induced killer (CIK) cells are an ex vivo expanded heterogeneous cell population with an enriched NK-T phenotype (CD3+CD56+). Due to the convenient and relatively inexpensive expansion capability, together with low incidence of graft versus host disease (GVHD) in allogeneic cancer patients,...

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Detalles Bibliográficos
Autores principales: Wu, Xiaolong, Sharma, Amit, Oldenburg, Johannes, Weiher, Hans, Essler, Markus, Skowasch, Dirk, Schmidt-Wolf, Ingo G. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8529192/
https://www.ncbi.nlm.nih.gov/pubmed/34691037
http://dx.doi.org/10.3389/fimmu.2021.731767