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DARPP-32 promotes ERBB3-mediated resistance to molecular targeted therapy in EGFR-mutated lung adenocarcinoma

Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI)-refractory lung adenocarcinoma (LUAD) progression is a major clinical problem. New approaches to predict and prevent acquired resistance to EGFR TKIs are urgently needed. Here, we show that dopamine and cyclic AMP-regulated phos...

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Detalles Bibliográficos
Autores principales:	Alam, Sk. Kayum, Zhang, Yongchang, Wang, Li, Zhu, Zhu, Hernandez, Christina E., Zhou, Yuling, Yang, Nong, Lei, Jian, Chen, Xiaoyan, Zeng, Liang, Klein, Mark A., Hoeppner, Luke H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8529229/ https://www.ncbi.nlm.nih.gov/pubmed/34675407 http://dx.doi.org/10.1038/s41388-021-02028-5

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