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A Large Neighbourhood Search Metaheuristic for the Contagious Disease Testing Problem

In late 2019 a new coronavirus disease (COVID-19) emerged, causing a global pandemic within only a few weeks. A crucial factor in the public health response to pandemics is achieving a short turnaround time between a potential case becoming known, specimen collection and availability of a test resul...

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Autores principales: Wolfinger, David, Gansterer, Margaretha, Doerner, Karl F., Popper, Nikolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier B.V. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8529256/
https://www.ncbi.nlm.nih.gov/pubmed/34697518
http://dx.doi.org/10.1016/j.ejor.2021.10.028
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author Wolfinger, David
Gansterer, Margaretha
Doerner, Karl F.
Popper, Nikolas
author_facet Wolfinger, David
Gansterer, Margaretha
Doerner, Karl F.
Popper, Nikolas
author_sort Wolfinger, David
collection PubMed
description In late 2019 a new coronavirus disease (COVID-19) emerged, causing a global pandemic within only a few weeks. A crucial factor in the public health response to pandemics is achieving a short turnaround time between a potential case becoming known, specimen collection and availability of a test result. In this article we address a logistics problem that arises in the context of testing potential cases. We assume that specimens can be collected in two ways: either by means of a mobile test-team or by means of a stationary test-team in a test-centre. After the specimens have been collected they must be delivered to a laboratory in order to be analysed. The problem we address aims at deciding how many test-centres to open and where, how many mobile test-teams to use, which suspected cases to assign to a test-centre and which to visit with a mobile test-team, which specimen to assign to which laboratory, and planning the routes of the mobile test-teams. The objective is to minimise the total cost of opening test-centres and routing mobile test-teams. We introduce this new problem, which we call the contagious disease testing problem (CDTP), and present a mixed-integer linear-programming formulation for it. We propose a large neighbourhood search metaheuristic for solving the CDTP and present an extensive computational study to illustrate its performance. Furthermore, we give managerial insights regarding COVID-19 test logistics, derived from problem instances based on real world data.
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spelling pubmed-85292562021-10-21 A Large Neighbourhood Search Metaheuristic for the Contagious Disease Testing Problem Wolfinger, David Gansterer, Margaretha Doerner, Karl F. Popper, Nikolas Eur J Oper Res Article In late 2019 a new coronavirus disease (COVID-19) emerged, causing a global pandemic within only a few weeks. A crucial factor in the public health response to pandemics is achieving a short turnaround time between a potential case becoming known, specimen collection and availability of a test result. In this article we address a logistics problem that arises in the context of testing potential cases. We assume that specimens can be collected in two ways: either by means of a mobile test-team or by means of a stationary test-team in a test-centre. After the specimens have been collected they must be delivered to a laboratory in order to be analysed. The problem we address aims at deciding how many test-centres to open and where, how many mobile test-teams to use, which suspected cases to assign to a test-centre and which to visit with a mobile test-team, which specimen to assign to which laboratory, and planning the routes of the mobile test-teams. The objective is to minimise the total cost of opening test-centres and routing mobile test-teams. We introduce this new problem, which we call the contagious disease testing problem (CDTP), and present a mixed-integer linear-programming formulation for it. We propose a large neighbourhood search metaheuristic for solving the CDTP and present an extensive computational study to illustrate its performance. Furthermore, we give managerial insights regarding COVID-19 test logistics, derived from problem instances based on real world data. The Author(s). Published by Elsevier B.V. 2023-01-01 2021-10-21 /pmc/articles/PMC8529256/ /pubmed/34697518 http://dx.doi.org/10.1016/j.ejor.2021.10.028 Text en © 2021 The Author(s) Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Wolfinger, David
Gansterer, Margaretha
Doerner, Karl F.
Popper, Nikolas
A Large Neighbourhood Search Metaheuristic for the Contagious Disease Testing Problem
title A Large Neighbourhood Search Metaheuristic for the Contagious Disease Testing Problem
title_full A Large Neighbourhood Search Metaheuristic for the Contagious Disease Testing Problem
title_fullStr A Large Neighbourhood Search Metaheuristic for the Contagious Disease Testing Problem
title_full_unstemmed A Large Neighbourhood Search Metaheuristic for the Contagious Disease Testing Problem
title_short A Large Neighbourhood Search Metaheuristic for the Contagious Disease Testing Problem
title_sort large neighbourhood search metaheuristic for the contagious disease testing problem
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8529256/
https://www.ncbi.nlm.nih.gov/pubmed/34697518
http://dx.doi.org/10.1016/j.ejor.2021.10.028
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