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Collagen Fragments Produced in Cancer Mediate T Cell Suppression Through Leukocyte-Associated Immunoglobulin-Like Receptor 1

The tumor microenvironment (TME) is a complex structure comprised of tumor, immune and stromal cells, vasculature, and extracellular matrix (ECM). During tumor development, ECM homeostasis is dysregulated. Collagen remodeling by matrix metalloproteinases (MMPs) generates specific collagen fragments,...

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Detalles Bibliográficos
Autores principales: Vijver, Saskia V., Singh, Akashdip, Mommers-Elshof, Eline T. A. M., Meeldijk, Jan, Copeland, Ronald, Boon, Louis, Langermann, Sol, Flies, Dallas, Meyaard, Linde, Ramos, M. Inês Pascoal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8529287/
https://www.ncbi.nlm.nih.gov/pubmed/34691040
http://dx.doi.org/10.3389/fimmu.2021.733561