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Collagen Fragments Produced in Cancer Mediate T Cell Suppression Through Leukocyte-Associated Immunoglobulin-Like Receptor 1
The tumor microenvironment (TME) is a complex structure comprised of tumor, immune and stromal cells, vasculature, and extracellular matrix (ECM). During tumor development, ECM homeostasis is dysregulated. Collagen remodeling by matrix metalloproteinases (MMPs) generates specific collagen fragments,...
Autores principales: | Vijver, Saskia V., Singh, Akashdip, Mommers-Elshof, Eline T. A. M., Meeldijk, Jan, Copeland, Ronald, Boon, Louis, Langermann, Sol, Flies, Dallas, Meyaard, Linde, Ramos, M. Inês Pascoal |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8529287/ https://www.ncbi.nlm.nih.gov/pubmed/34691040 http://dx.doi.org/10.3389/fimmu.2021.733561 |
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