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Targeting the Mycobacterium tuberculosis Stringent Response as a Strategy for Shortening Tuberculosis Treatment

The stringent response is well conserved across bacterial species and is a key pathway involved both in bacterial survival and virulence and in the induction of antibiotic tolerance in Mycobacteria. It is mediated by the alarmone (p)ppGpp and the regulatory molecule inorganic polyphosphate in respon...

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Detalles Bibliográficos
Autores principales: Danchik, Carina, Wang, Siqing, Karakousis, Petros C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8529327/
https://www.ncbi.nlm.nih.gov/pubmed/34690990
http://dx.doi.org/10.3389/fmicb.2021.744167