Expression of p16 Within Myenteric Neurons of the Aged Colon: A Potential Marker of Declining Function

Human colonic neuromuscular functions decline among the elderly. The aim was to explore the involvement of senescence. A preliminary PCR study looked for age-dependent differences in expression of CDKN1A (encoding the senescence-related p21 protein) and CDKN2A (encoding p16 and p14) in human ascendi...

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Detalles Bibliográficos
Autores principales: Palmer, Alexandra, Epton, Sarah, Crawley, Ellie, Straface, Marilisa, Gammon, Luke, Edgar, Meghan M., Xu, Yichen, Elahi, Shezan, Chin-Aleong, Joanne, Martin, Joanne E., Bishop, Cleo L., Knowles, Charles H., Sanger, Gareth J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8529329/
https://www.ncbi.nlm.nih.gov/pubmed/34690683
http://dx.doi.org/10.3389/fnins.2021.747067

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