Nosocomial cluster of carbapenemase-producing Enterobacter cloacae in an intensive care unit dedicated COVID-19

Concomitant prevention of SARS-CoV-2 and extensively drug-resistant bacteria transmission is a difficult challenge in intensive care units dedicated to COVID-19 patients. We report a nosocomial cluster of four patients carrying NDM-1 plasmid-encoded carbapenemase-producing Enterobacter cloacae. Two...

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Autores principales: Miltgen, Guillaume, Garrigos, Thomas, Cholley, Pascal, Deleume, Marine, Allou, Nicolas, Allyn, Jérôme, Wilkinson, David A., Lugagne, Nathalie, Belmonte, Olivier, Bertrand, Xavier, Hocquet, Didier, Mavingui, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8529563/
https://www.ncbi.nlm.nih.gov/pubmed/34674756
http://dx.doi.org/10.1186/s13756-021-01022-6
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author Miltgen, Guillaume
Garrigos, Thomas
Cholley, Pascal
Deleume, Marine
Allou, Nicolas
Allyn, Jérôme
Wilkinson, David A.
Lugagne, Nathalie
Belmonte, Olivier
Bertrand, Xavier
Hocquet, Didier
Mavingui, Patrick
author_facet Miltgen, Guillaume
Garrigos, Thomas
Cholley, Pascal
Deleume, Marine
Allou, Nicolas
Allyn, Jérôme
Wilkinson, David A.
Lugagne, Nathalie
Belmonte, Olivier
Bertrand, Xavier
Hocquet, Didier
Mavingui, Patrick
author_sort Miltgen, Guillaume
collection PubMed
description Concomitant prevention of SARS-CoV-2 and extensively drug-resistant bacteria transmission is a difficult challenge in intensive care units dedicated to COVID-19 patients. We report a nosocomial cluster of four patients carrying NDM-1 plasmid-encoded carbapenemase-producing Enterobacter cloacae. Two main factors may have contributed to cross-transmission: misuse of gloves and absence of change of personal protective equipment, in the context of COVID-19-associated shortage. This work highlights the importance of maintaining infection control measures to prevent CPE cross-transmission despite the difficult context and that this type of outbreak can potentially involve several species of Enterobacterales. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s13756-021-01022-6.
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spelling pubmed-85295632021-10-21 Nosocomial cluster of carbapenemase-producing Enterobacter cloacae in an intensive care unit dedicated COVID-19 Miltgen, Guillaume Garrigos, Thomas Cholley, Pascal Deleume, Marine Allou, Nicolas Allyn, Jérôme Wilkinson, David A. Lugagne, Nathalie Belmonte, Olivier Bertrand, Xavier Hocquet, Didier Mavingui, Patrick Antimicrob Resist Infect Control Short Report Concomitant prevention of SARS-CoV-2 and extensively drug-resistant bacteria transmission is a difficult challenge in intensive care units dedicated to COVID-19 patients. We report a nosocomial cluster of four patients carrying NDM-1 plasmid-encoded carbapenemase-producing Enterobacter cloacae. Two main factors may have contributed to cross-transmission: misuse of gloves and absence of change of personal protective equipment, in the context of COVID-19-associated shortage. This work highlights the importance of maintaining infection control measures to prevent CPE cross-transmission despite the difficult context and that this type of outbreak can potentially involve several species of Enterobacterales. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s13756-021-01022-6. BioMed Central 2021-10-21 /pmc/articles/PMC8529563/ /pubmed/34674756 http://dx.doi.org/10.1186/s13756-021-01022-6 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Short Report
Miltgen, Guillaume
Garrigos, Thomas
Cholley, Pascal
Deleume, Marine
Allou, Nicolas
Allyn, Jérôme
Wilkinson, David A.
Lugagne, Nathalie
Belmonte, Olivier
Bertrand, Xavier
Hocquet, Didier
Mavingui, Patrick
Nosocomial cluster of carbapenemase-producing Enterobacter cloacae in an intensive care unit dedicated COVID-19
title Nosocomial cluster of carbapenemase-producing Enterobacter cloacae in an intensive care unit dedicated COVID-19
title_full Nosocomial cluster of carbapenemase-producing Enterobacter cloacae in an intensive care unit dedicated COVID-19
title_fullStr Nosocomial cluster of carbapenemase-producing Enterobacter cloacae in an intensive care unit dedicated COVID-19
title_full_unstemmed Nosocomial cluster of carbapenemase-producing Enterobacter cloacae in an intensive care unit dedicated COVID-19
title_short Nosocomial cluster of carbapenemase-producing Enterobacter cloacae in an intensive care unit dedicated COVID-19
title_sort nosocomial cluster of carbapenemase-producing enterobacter cloacae in an intensive care unit dedicated covid-19
topic Short Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8529563/
https://www.ncbi.nlm.nih.gov/pubmed/34674756
http://dx.doi.org/10.1186/s13756-021-01022-6
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