Visualizing Teixobactin Supramolecular Assemblies and Cell Wall Damage in B. Subtilis Using CryoEM

[Image: see text] The antibiotic teixobactin targets bacterial cell walls. Previous research has proposed that the active form of teixobactin is a nano-/micron-sized supramolecular assembly. Here, we use cryogenic transmission electron microscopy to show that at 1 mg/mL, teixobactin forms sheet-like...

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Detalles Bibliográficos
Autores principales: Hurst, Paul Joshua, Morris, Michael A., Graham, Annissa A., Nowick, James S., Patterson, Joseph P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8529686/
https://www.ncbi.nlm.nih.gov/pubmed/34693162
http://dx.doi.org/10.1021/acsomega.1c04331

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8529686/
https://www.ncbi.nlm.nih.gov/pubmed/34693162
http://dx.doi.org/10.1021/acsomega.1c04331

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