Cargando…
Visualizing Teixobactin Supramolecular Assemblies and Cell Wall Damage in B. Subtilis Using CryoEM
[Image: see text] The antibiotic teixobactin targets bacterial cell walls. Previous research has proposed that the active form of teixobactin is a nano-/micron-sized supramolecular assembly. Here, we use cryogenic transmission electron microscopy to show that at 1 mg/mL, teixobactin forms sheet-like...
Autores principales: | Hurst, Paul Joshua, Morris, Michael A., Graham, Annissa A., Nowick, James S., Patterson, Joseph P. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2021
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8529686/ https://www.ncbi.nlm.nih.gov/pubmed/34693162 http://dx.doi.org/10.1021/acsomega.1c04331 |
Ejemplares similares
-
Visualizing the mode of action and supramolecular assembly of teixobactin analogues in Bacillus subtilis
por: Morris, Michael A., et al.
Publicado: (2022) -
CryoEM structure of the Nipah virus nucleocapsid assembly
por: Ker, De-Sheng, et al.
Publicado: (2021) -
AlphaFold2 and CryoEM: Revisiting CryoEM modeling in near-atomic resolution density maps
por: Hryc, Corey F., et al.
Publicado: (2022) -
Isobactins: O-acyl isopeptide prodrugs of teixobactin and teixobactin derivatives
por: Jones, Chelsea R., et al.
Publicado: (2022) -
Time-resolved cryoEM using Spotiton
por: Dandey, Venkata P., et al.
Publicado: (2020)