The mitochondrially-localized nucleoside diphosphate kinase D (NME4) is a novel metastasis suppressor

BACKGROUND: Mitochondrial nucleoside diphosphate kinase (NDPK-D, NME4, NM23-H4) is a multifunctional enzyme mainly localized in the intermembrane space, bound to the inner membrane. RESULTS: We constructed loss-of-function mutants of NDPK-D, lacking either NDP kinase activity or membrane interaction...

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Detalles Bibliográficos
Autores principales: Lacombe, Marie-Lise, Lamarche, Frederic, De Wever, Olivier, Padilla-Benavides, Teresita, Carlson, Alyssa, Khan, Imran, Huna, Anda, Vacher, Sophie, Calmel, Claire, Desbourdes, Céline, Cottet-Rousselle, Cécile, Hininger-Favier, Isabelle, Attia, Stéphane, Nawrocki-Raby, Béatrice, Raingeaud, Joël, Machon, Christelle, Guitton, Jérôme, Le Gall, Morgane, Clary, Guilhem, Broussard, Cedric, Chafey, Philippe, Thérond, Patrice, Bernard, David, Fontaine, Eric, Tokarska-Schlattner, Malgorzata, Steeg, Patricia, Bièche, Ivan, Schlattner, Uwe, Boissan, Mathieu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8529772/
https://www.ncbi.nlm.nih.gov/pubmed/34674701
http://dx.doi.org/10.1186/s12915-021-01155-5

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