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High-throughput and affordable genome-wide methylation profiling of circulating cell-free DNA by methylated DNA sequencing (MeD-seq) of LpnPI digested fragments

BACKGROUND: DNA methylation detection in liquid biopsies provides a highly promising and much needed means for real-time monitoring of disease load in advanced cancer patient care. Compared to the often-used somatic mutations, tissue- and cancer-type specific epigenetic marks affect a larger part of...

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Detalles Bibliográficos
Autores principales:	Deger, Teoman, Boers, Ruben G., de Weerd, Vanja, Angus, Lindsay, van der Put, Marjolijn M. J., Boers, Joachim B., Azmani, Z., van IJcken, Wilfred F. J., Grünhagen, Dirk J., van Dessel, Lisanne F., Lolkema, Martijn P. J. K., Verhoef, Cornelis, Sleijfer, Stefan, Martens, John W. M., Gribnau, Joost, Wilting, Saskia M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8529776/ https://www.ncbi.nlm.nih.gov/pubmed/34670587 http://dx.doi.org/10.1186/s13148-021-01177-4

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