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Systemic administration of choline acetyltransferase decreases blood pressure in murine hypertension

Acetylcholine (ACh) decreases blood pressure by stimulating endothelium nitric oxide-dependent vasodilation in resistance arterioles. Normal plasma contains choline acetyltransferase (ChAT) and its biosynthetic product ACh at appreciable concentrations to potentially act upon the endothelium to affe...

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Detalles Bibliográficos
Autores principales:	Stiegler, Andrew, Li, Jian-Hua, Shah, Vivek, Tsaava, Tea, Tynan, Aisling, Yang, Huan, Tamari, Yehuda, Brines, Michael, Tracey, Kevin J., Chavan, Sangeeta S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8529785/ https://www.ncbi.nlm.nih.gov/pubmed/34674633 http://dx.doi.org/10.1186/s10020-021-00380-6

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