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AZD2014, a dual mTOR inhibitor, attenuates cardiac hypertrophy in vitro and in vivo

Cardiac hypertrophy is one of the most common genetic heart disorders and considered a risk factor for cardiac morbidity and mortality. The mammalian target of rapamycin (mTOR) pathway plays a key regulatory function in cardiovascular physiology and pathology in hypertrophy. AZD2014 is a small-molec...

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Detalles Bibliográficos
Autores principales:	Cha, Byung-Hyun, Jung, Minjin, Kim, Angela S., Lepak, Victoria C., Colson, Brett A., Bull, David A., Won, Youngwook
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8529824/ https://www.ncbi.nlm.nih.gov/pubmed/34674743 http://dx.doi.org/10.1186/s13036-021-00276-3

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