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Red Blood Cell and Endothelial eNOS Independently Regulate Circulating Nitric Oxide Metabolites and Blood Pressure

Current paradigms suggest that nitric oxide (NO) produced by endothelial cells (ECs) through endothelial nitric oxide synthase (eNOS) in the vessel wall is the primary regulator of blood flow and blood pressure. However, red blood cells (RBCs) also carry a catalytically active eNOS, but its role is...

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Detalles Bibliográficos
Autores principales: Leo, Francesca, Suvorava, Tatsiana, Heuser, Sophia K., Li, Junjie, LoBue, Anthea, Barbarino, Frederik, Piragine, Eugenia, Schneckmann, Rebekka, Hutzler, Beate, Good, Miranda E., Fernandez, Bernadette O., Vornholz, Lukas, Rogers, Stephen, Doctor, Allan, Grandoch, Maria, Stegbauer, Johannes, Weitzberg, Eddie, Feelisch, Martin, Lundberg, Jon O., Isakson, Brant E., Kelm, Malte, Cortese-Krott, Miriam M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8529898/
https://www.ncbi.nlm.nih.gov/pubmed/34229449
http://dx.doi.org/10.1161/CIRCULATIONAHA.120.049606