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Red Blood Cell and Endothelial eNOS Independently Regulate Circulating Nitric Oxide Metabolites and Blood Pressure
Current paradigms suggest that nitric oxide (NO) produced by endothelial cells (ECs) through endothelial nitric oxide synthase (eNOS) in the vessel wall is the primary regulator of blood flow and blood pressure. However, red blood cells (RBCs) also carry a catalytically active eNOS, but its role is...
Autores principales: | Leo, Francesca, Suvorava, Tatsiana, Heuser, Sophia K., Li, Junjie, LoBue, Anthea, Barbarino, Frederik, Piragine, Eugenia, Schneckmann, Rebekka, Hutzler, Beate, Good, Miranda E., Fernandez, Bernadette O., Vornholz, Lukas, Rogers, Stephen, Doctor, Allan, Grandoch, Maria, Stegbauer, Johannes, Weitzberg, Eddie, Feelisch, Martin, Lundberg, Jon O., Isakson, Brant E., Kelm, Malte, Cortese-Krott, Miriam M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8529898/ https://www.ncbi.nlm.nih.gov/pubmed/34229449 http://dx.doi.org/10.1161/CIRCULATIONAHA.120.049606 |
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