Radiotherapy for gastric mucosa-associated lymphoid tissue lymphoma

Gastric mucosa-associated lymphoid tissue (MALT) lymphoma is a rare disease which is often associated with Helicobacter pylori (H. pylori) infection. First-line treatment of stage IE and IIE localized gastric MALT lymphoma is based on the eradication of H. pylori. The presence of H. pylori resistanc...

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Autores principales: Quéro, Laurent, Labidi, Mouna, Bollet, Marc, Bommier, Côme, Guillerm, Sophie, Hennequin, Christophe, Thieblemont, Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2021
Materias:
Minireviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8529931/
https://www.ncbi.nlm.nih.gov/pubmed/34721777
http://dx.doi.org/10.4251/wjgo.v13.i10.1453
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author Quéro, Laurent
Labidi, Mouna
Bollet, Marc
Bommier, Côme
Guillerm, Sophie
Hennequin, Christophe
Thieblemont, Catherine
author_facet Quéro, Laurent
Labidi, Mouna
Bollet, Marc
Bommier, Côme
Guillerm, Sophie
Hennequin, Christophe
Thieblemont, Catherine
author_sort Quéro, Laurent
collection PubMed
description Gastric mucosa-associated lymphoid tissue (MALT) lymphoma is a rare disease which is often associated with Helicobacter pylori (H. pylori) infection. First-line treatment of stage IE and IIE localized gastric MALT lymphoma is based on the eradication of H. pylori. The presence of H. pylori resistance factors such as translocation t (11;18), peri-gastric lymph node involvement and the degree of tumor infiltration of the gastric wall; or lack of response to antibiotic therapy are two main indications to treat with definitive radiotherapy (RT). RT is an effective treatment in localized gastric MALT lymphoma. A moderate dose of 30 Gy allows a high cure rate while being well tolerated. After treatment, regular gastric endoscopic follow-up is necessary to detect a potential occurrence of gastric adenocarcinoma.
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spelling pubmed-85299312021-10-28 Radiotherapy for gastric mucosa-associated lymphoid tissue lymphoma Quéro, Laurent Labidi, Mouna Bollet, Marc Bommier, Côme Guillerm, Sophie Hennequin, Christophe Thieblemont, Catherine World J Gastrointest Oncol Minireviews Gastric mucosa-associated lymphoid tissue (MALT) lymphoma is a rare disease which is often associated with Helicobacter pylori (H. pylori) infection. First-line treatment of stage IE and IIE localized gastric MALT lymphoma is based on the eradication of H. pylori. The presence of H. pylori resistance factors such as translocation t (11;18), peri-gastric lymph node involvement and the degree of tumor infiltration of the gastric wall; or lack of response to antibiotic therapy are two main indications to treat with definitive radiotherapy (RT). RT is an effective treatment in localized gastric MALT lymphoma. A moderate dose of 30 Gy allows a high cure rate while being well tolerated. After treatment, regular gastric endoscopic follow-up is necessary to detect a potential occurrence of gastric adenocarcinoma. Baishideng Publishing Group Inc 2021-10-15 2021-10-15 /pmc/articles/PMC8529931/ /pubmed/34721777 http://dx.doi.org/10.4251/wjgo.v13.i10.1453 Text en ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. https://creativecommons.org/licenses/by-nc/4.0/This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
spellingShingle Minireviews
Quéro, Laurent
Labidi, Mouna
Bollet, Marc
Bommier, Côme
Guillerm, Sophie
Hennequin, Christophe
Thieblemont, Catherine
Radiotherapy for gastric mucosa-associated lymphoid tissue lymphoma
title Radiotherapy for gastric mucosa-associated lymphoid tissue lymphoma
title_full Radiotherapy for gastric mucosa-associated lymphoid tissue lymphoma
title_fullStr Radiotherapy for gastric mucosa-associated lymphoid tissue lymphoma
title_full_unstemmed Radiotherapy for gastric mucosa-associated lymphoid tissue lymphoma
title_short Radiotherapy for gastric mucosa-associated lymphoid tissue lymphoma
title_sort radiotherapy for gastric mucosa-associated lymphoid tissue lymphoma
topic Minireviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8529931/
https://www.ncbi.nlm.nih.gov/pubmed/34721777
http://dx.doi.org/10.4251/wjgo.v13.i10.1453
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