Cargando…

CD19 CAR-T Cells With Membrane-Bound IL-15 for B-Cell Acute Lymphoblastic Leukemia After Failure of CD19 and CD22 CAR-T Cells: Case Report

OBJECTIVES: At present, reinfusions of chimeric antigen receptor (CAR)-T cell have exhibited limited efficacy, while their efficacy on extramedullary relapse remains to be further elucidated in B-cell acute lymphoblastic leukemia (B-ALL). Although combination with IL-15 demonstrated the potential to...

Descripción completa

Detalles Bibliográficos
Autores principales: Sun, Yao, Su, Yongfeng, Wang, Yizhi, Liu, Na, Li, Yuhang, Chen, Jianlin, Qiao, Zhuoqing, Niu, Jingwen, Hu, Jiangwei, Zhang, Bin, Ning, Hongmei, Hu, Liangding
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8530183/
https://www.ncbi.nlm.nih.gov/pubmed/34691036
http://dx.doi.org/10.3389/fimmu.2021.728962