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CD19 CAR-T Cells With Membrane-Bound IL-15 for B-Cell Acute Lymphoblastic Leukemia After Failure of CD19 and CD22 CAR-T Cells: Case Report

OBJECTIVES: At present, reinfusions of chimeric antigen receptor (CAR)-T cell have exhibited limited efficacy, while their efficacy on extramedullary relapse remains to be further elucidated in B-cell acute lymphoblastic leukemia (B-ALL). Although combination with IL-15 demonstrated the potential to...

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Detalles Bibliográficos
Autores principales:	Sun, Yao, Su, Yongfeng, Wang, Yizhi, Liu, Na, Li, Yuhang, Chen, Jianlin, Qiao, Zhuoqing, Niu, Jingwen, Hu, Jiangwei, Zhang, Bin, Ning, Hongmei, Hu, Liangding
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8530183/ https://www.ncbi.nlm.nih.gov/pubmed/34691036 http://dx.doi.org/10.3389/fimmu.2021.728962

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