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Matrix Stiffness Affects Glycocalyx Expression in Cultured Endothelial Cells

Rationale: The endothelial cell glycocalyx (GCX) is a mechanosensor that plays a key role in protecting against vascular diseases. We have previously shown that age/disease mediated matrix stiffness inhibits the glycocalyx glycosaminoglycan heparan sulfate and its core protein Glypican 1 in human um...

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Detalles Bibliográficos
Autores principales: Mahmoud, Marwa, Cancel, Limary, Tarbell, John M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8530223/
https://www.ncbi.nlm.nih.gov/pubmed/34692689
http://dx.doi.org/10.3389/fcell.2021.731666

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