The staying power of hematopoietic stem cells

Hematopoietic stem and progenitor cells (HSPCs) use specialized adhesive structures referred to as magnupodium to stay in hematopoietic niches. Bessey et al. (2021. J. Cell Biol. https://doi.org/10.1083/jcb.202005085) define new characteristics of the magnupodium, including centriole polarization an...

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Detalles Bibliográficos
Autor principal: Dustin, Michael L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Spotlight
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8530228/
https://www.ncbi.nlm.nih.gov/pubmed/34661601
http://dx.doi.org/10.1083/jcb.202109019
Descripción
Sumario:Hematopoietic stem and progenitor cells (HSPCs) use specialized adhesive structures referred to as magnupodium to stay in hematopoietic niches. Bessey et al. (2021. J. Cell Biol. https://doi.org/10.1083/jcb.202005085) define new characteristics of the magnupodium, including centriole polarization and the necessary and sufficient role of CXCR4 signaling.

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