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Improved prediction of smoking status via isoform-aware RNA-seq deep learning models
Most predictive models based on gene expression data do not leverage information related to gene splicing, despite the fact that splicing is a fundamental feature of eukaryotic gene expression. Cigarette smoking is an important environmental risk factor for many diseases, and it has profound effects...
Autores principales: | Wang, Zifeng, Masoomi, Aria, Xu, Zhonghui, Boueiz, Adel, Lee, Sool, Zhao, Tingting, Bowler, Russell, Cho, Michael, Silverman, Edwin K., Hersh, Craig, Dy, Jennifer, Castaldi, Peter J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8530282/ https://www.ncbi.nlm.nih.gov/pubmed/34634029 http://dx.doi.org/10.1371/journal.pcbi.1009433 |
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