Cargando…
TRPV4 is activated by mechanical stimulation to induce prostaglandins release in trabecular meshwork, lowering intraocular pressure
Trabecular meshwork constitutes the conventional outflow pathway and controls intraocular pressure by regulating aqueous outflow. Mechanical stimulation has been studied as one of the triggers to regulate aqueous outflow in trabecular meshwork, but it is not well understood. We investigated that how...
Autores principales: | Uchida, Takatoshi, Shimizu, Shota, Yamagishi, Reiko, Tokuoka, Suzumi M., Kita, Yoshihiro, Sakata, Rei, Honjo, Megumi, Aihara, Makoto |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8530296/ https://www.ncbi.nlm.nih.gov/pubmed/34673834 http://dx.doi.org/10.1371/journal.pone.0258911 |
Ejemplares similares
-
Mechanical stretch induces Ca(2+) influx and extracellular release of PGE(2) through Piezo1 activation in trabecular meshwork cells
por: Uchida, Takatoshi, et al.
Publicado: (2021) -
Effects of selective EP2 receptor agonist, omidenepag, on trabecular meshwork cells, Schlemm’s canal endothelial cells and ciliary muscle contraction
por: Nakamura, Natsuko, et al.
Publicado: (2021) -
Effect of pigmentation intensity of trabecular meshwork cells on mechanisms of micropulse laser trabeculoplasty
por: Shimizu, Shota, et al.
Publicado: (2022) -
Crosstalk between transforming growth factor β-2 and Autotaxin in trabecular meshwork and different subtypes of glaucoma
por: Igarashi, Nozomi, et al.
Publicado: (2021) -
Fibrotic Response of Human Trabecular Meshwork Cells to Transforming Growth Factor-Beta 3 and Autotaxin in Aqueous Humor
por: Liu, Mengxuan, et al.
Publicado: (2022)