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Potential of mucoadhesive chitosan glutamate microparticles as microbicide carriers – antiherpes activity and penetration behavior across the human vaginal epithelium

Chitosan glutamate (gCS) spray-dried microparticles appear promising carriers to overcome challenges associated with vaginal microbicide delivery. This study aimed at elucidating the penetration and mucoadhesive behavior of developed gCS multiunit carriers with zidovudine (ZVD) as a model antiretrov...

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Detalles Bibliográficos
Autores principales: Szymańska, Emilia, Krzyżowska, Małgorzata, Cal, Krzysztof, Mikolaszek, Barbara, Tomaszewski, Jakub, Wołczyński, Sławomir, Winnicka, Katarzyna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8530489/
https://www.ncbi.nlm.nih.gov/pubmed/34668816
http://dx.doi.org/10.1080/10717544.2021.1992037